Swelling after Robenacoxib (Onsior) in dogs

The FDA has received 24 reports of swelling in dogs after Robenacoxib. That is 21% of all reports for this medicine, compared with 2.8% across reports for all dog medicines, so it is reported unusually often with this medicine.

24Reports

0.0%Marked serious

17%Recovered

0.0%Died or euthanised

Same dayTypical onset

How soon it started

Same day

18 78%

1–2 days

1 4.3%

3–7 days

1 4.3%

1–4 weeks

2 8.7%

Over a month

1 4.3%

How the animals did

Recovered

4 17%

Still unwell when reported

15 63%

Not known

5 21%

Problems reported at the same time

Injection site reaction

4 17%

Hyphaemia

2 8.3%

Decreased packed cell volume (pcv)

2 8.3%

Reddening of the skin

2 8.3%

Abnormal menace reflex test

2 8.3%

Eye inflammation

2 8.3%

Decreased intra-ocular pressure

2 8.3%

Conjunctival irritation

2 8.3%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Robenacoxib relieves pain and inflammation (short courses).

Products with this ingredient include Onsior. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

NSAIDs can affect the stomach, liver and kidneys. Vets usually recommend blood tests before and during long-term use.

Questions owners ask

Can Robenacoxib cause swelling in dogs?: 24 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within the same day of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Swelling with similar medicines

Swelling after Carprofen (Rimadyl) 2,497 reports · 5.3% of its reports
Swelling after Deracoxib (Deramaxx) 469 reports · 4.3% of its reports
Swelling after Grapiprant (Galliprant) 188 reports · 2.1% of its reports
Swelling after Meloxicam (Metacam) 431 reports · 5.3% of its reports
Swelling after Firocoxib (Previcox) 300 reports · 3.7% of its reports

All reported side effects of Robenacoxib in dogs · Medicines most reported with swelling