Hyperphosphataemia after Rabies Vaccine in dogs

The FDA has received 143 reports of hyperphosphataemia in dogs after Rabies Vaccine. That is 1.4% of all reports for this medicine, compared with 0.6% across reports for all dog medicines, so it is reported unusually often with this medicine.

143Reports
89%Marked serious
7.7%Recovered
48%Died or euthanised
3 daysTypical onset
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How soon it started

Same day
25 20%
1–2 days
30 24%
3–7 days
20 16%
1–4 weeks
29 24%
Over a month
19 15%

How the animals did

Recovered
9 6.3%
Recovered with lasting effects
2 1.4%
Still unwell when reported
42 29%
Died
19 13%
Euthanised
49 34%
Not known
22 15%

Problems reported at the same time

Age of the animals

Under 1 year
29
1–3 years
25
4–7 years
32
8–11 years
32
12+ years
25

About this medicine

Type: vaccine.

Mild, short-lived lethargy, soreness or a small lump at the injection site are the most commonly reported vaccine reactions.

Questions owners ask

Can Rabies Vaccine cause hyperphosphataemia in dogs?
143 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 3 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Hyperphosphataemia with similar medicines

All reported side effects of Rabies Vaccine in dogs · Medicines most reported with hyperphosphataemia