Elevated gamma-glutamyl transferase (ggt) after Rabies Vaccine in dogs

The FDA has received 68 reports of elevated gamma-glutamyl transferase (ggt) in dogs after Rabies Vaccine. That is 0.7% of all reports for this medicine, compared with 0.4% across reports for all dog medicines, so it is reported unusually often with this medicine.

68Reports
84%Marked serious
15%Recovered
28%Died or euthanised
7 daysTypical onset
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How soon it started

Same day
15 27%
1–2 days
7 13%
3–7 days
10 18%
1–4 weeks
11 20%
Over a month
13 23%

How the animals did

Recovered
9 13%
Recovered with lasting effects
1 1.5%
Still unwell when reported
29 43%
Died
6 8.8%
Euthanised
13 19%
Not known
10 15%

Problems reported at the same time

Liver problems
59 87%
Loss of appetite
43 63%
Vomiting
35 51%
Lethargy
30 44%
Kidney problems
22 32%
Death
20 29%
Blood problems
18 26%
Leucocytosis
16 24%

Age of the animals

Under 1 year
9
1–3 years
15
4–7 years
16
8–11 years
22
12+ years
6

About this medicine

Type: vaccine.

Mild, short-lived lethargy, soreness or a small lump at the injection site are the most commonly reported vaccine reactions.

Questions owners ask

Can Rabies Vaccine cause elevated gamma-glutamyl transferase (ggt) in dogs?
68 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 7 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Elevated gamma-glutamyl transferase (ggt) with similar medicines

All reported side effects of Rabies Vaccine in dogs · Medicines most reported with elevated gamma-glutamyl transferase (ggt)