Elevated gamma-glutamyl transferase (ggt) after Bordetella Vaccine in dogs

The FDA has received 43 reports of elevated gamma-glutamyl transferase (ggt) in dogs after Bordetella Vaccine. That is 0.5% of all reports for this medicine, compared with 0.4% across reports for all dog medicines.

43Reports
77%Marked serious
16%Recovered
33%Died or euthanised
11 daysTypical onset
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How soon it started

Same day
10 28%
1–2 days
4 11%
3–7 days
3 8.3%
1–4 weeks
9 25%
Over a month
10 28%

How the animals did

Recovered
7 16%
Still unwell when reported
17 40%
Died
6 14%
Euthanised
8 19%
Not known
5 12%

Problems reported at the same time

Liver problems
37 86%
Vomiting
28 65%
Loss of appetite
26 60%
Lethargy
23 53%
Kidney problems
17 40%
Blood problems
15 35%
Death
14 33%
Diarrhea
11 26%

Age of the animals

Under 1 year
6
1–3 years
9
4–7 years
10
8–11 years
13
12+ years
5

About this medicine

Type: vaccine.

Mild, short-lived lethargy, soreness or a small lump at the injection site are the most commonly reported vaccine reactions.

Questions owners ask

Can Bordetella Vaccine cause elevated gamma-glutamyl transferase (ggt) in dogs?
43 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 11 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Elevated gamma-glutamyl transferase (ggt) with similar medicines

All reported side effects of Bordetella Vaccine in dogs · Medicines most reported with elevated gamma-glutamyl transferase (ggt)