Elevated amylase after Rabies Vaccine in dogs

The FDA has received 78 reports of elevated amylase in dogs after Rabies Vaccine. That is 0.8% of all reports for this medicine, compared with 0.3% across reports for all dog medicines, so it is reported unusually often with this medicine.

78Reports

87%Marked serious

9.0%Recovered

36%Died or euthanised

10 daysTypical onset

How soon it started

Same day

13 21%

1–2 days

3 4.8%

3–7 days

10 16%

1–4 weeks

19 30%

Over a month

18 29%

How the animals did

Recovered

6 7.7%

Recovered with lasting effects

1 1.3%

Still unwell when reported

25 32%

Died

11 14%

Euthanised

17 22%

Not known

18 23%

Problems reported at the same time

45 58%

44 56%

43 55%

42 54%

32 41%

30 38%

29 37%

29 37%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Type: vaccine.

Mild, short-lived lethargy, soreness or a small lump at the injection site are the most commonly reported vaccine reactions.

Questions owners ask

Can Rabies Vaccine cause elevated amylase in dogs?: 78 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 10 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Elevated amylase with similar medicines

Elevated amylase after Bordetella Vaccine 51 reports · 0.5% of its reports
Elevated amylase after Leptospirosis Vaccine 63 reports · 0.8% of its reports
Elevated amylase after Distemper-parvo Vaccine 50 reports · 0.8% of its reports

All reported side effects of Rabies Vaccine in dogs · Medicines most reported with elevated amylase