Behaviour change after Rabies Vaccine in dogs

The FDA has received 406 reports of behaviour change in dogs after Rabies Vaccine. That is 4.1% of all reports for this medicine, compared with 2.5% across reports for all dog medicines, so it is reported unusually often with this medicine.

406Reports
62%Marked serious
28%Recovered
17%Died or euthanised
2 daysTypical onset
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How soon it started

Same day
110 34%
1–2 days
64 20%
3–7 days
46 14%
1–4 weeks
47 15%
Over a month
56 17%

How the animals did

Recovered
99 24%
Recovered with lasting effects
16 3.9%
Still unwell when reported
136 33%
Died
35 8.6%
Euthanised
35 8.6%
Not known
85 21%

Problems reported at the same time

Age of the animals

Under 1 year
43
1–3 years
133
4–7 years
108
8–11 years
81
12+ years
36

About this medicine

Type: vaccine.

Mild, short-lived lethargy, soreness or a small lump at the injection site are the most commonly reported vaccine reactions.

Questions owners ask

Can Rabies Vaccine cause behaviour change in dogs?
406 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 2 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Behaviour change with similar medicines

All reported side effects of Rabies Vaccine in dogs · Medicines most reported with behaviour change