Hypoalbuminaemia after Prednisolone in dogs

34 reports to the FDA describe hypoalbuminaemia in dogs given Prednisolone. That is 2.8% of all reports for this medicine, compared with 0.6% across reports for all dog medicines, so it is reported unusually often with this medicine.

34Reports

82%Marked serious

0.0%Recovered

24%Died or euthanised

19 daysTypical onset

How soon it started

Same day

3 11%

1–2 days

2 7.4%

3–7 days

5 19%

1–4 weeks

6 22%

Over a month

11 41%

How the animals did

Still unwell when reported

18 53%

Died

2 5.9%

Euthanised

6 18%

Not known

8 24%

Problems reported at the same time

15 44%

14 41%

14 41%

13 38%

13 38%

Hypoproteinaemia

12 35%

Neutrophilia

12 35%

Leucocytosis

11 32%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Prednisolone reduces inflammation and immune activity.

Steroids commonly cause increased thirst, urination and appetite, especially at higher doses.

Questions owners ask

Can Prednisolone cause hypoalbuminaemia in dogs?: 34 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 19 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Hypoalbuminaemia with similar medicines

Hypoalbuminaemia after Prednisone 145 reports · 1.6% of its reports
Hypoalbuminaemia after Dexamethasone 99 reports · 3.6% of its reports
Hypoalbuminaemia after Prednisolone + Trimeprazine 21 reports · 1.0% of its reports

All reported side effects of Prednisolone in dogs · Medicines most reported with hypoalbuminaemia