Disorientation after Prednisolone in dogs

22 reports to the FDA describe disorientation in dogs given Prednisolone. That is 1.8% of all reports for this medicine, compared with 1.0% across reports for all dog medicines, so it is reported unusually often with this medicine.

22Reports

77%Marked serious

41%Recovered

27%Died or euthanised

8 daysTypical onset

How soon it started

Same day

5 29%

1–2 days

1 5.9%

3–7 days

2 12%

1–4 weeks

4 24%

Over a month

5 29%

How the animals did

Recovered

8 36%

Recovered with lasting effects

1 4.5%

Still unwell when reported

2 9.1%

Died

3 14%

Euthanised

3 14%

Not known

5 23%

Problems reported at the same time

8 36%

8 36%

7 32%

6 27%

6 27%

6 27%

6 27%

5 23%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Prednisolone reduces inflammation and immune activity.

Steroids commonly cause increased thirst, urination and appetite, especially at higher doses.

Questions owners ask

Can Prednisolone cause disorientation in dogs?: 22 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 8 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Disorientation with similar medicines

Disorientation after Prednisone 121 reports · 1.4% of its reports
Disorientation after Dexamethasone 52 reports · 1.9% of its reports
Disorientation after Prednisolone + Trimeprazine 34 reports · 1.6% of its reports

All reported side effects of Prednisolone in dogs · Medicines most reported with disorientation