Underdose after Phenobarbital in dogs

The FDA has received 35 reports of underdose in dogs after Phenobarbital. That is 2.3% of all reports for this medicine, compared with 1.0% across reports for all dog medicines, so it is reported unusually often with this medicine.

35Reports
40%Marked serious
23%Recovered
8.6%Died or euthanised
149 daysTypical onset
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How soon it started

Same day
4 19%
1–2 days
2 9.5%
3–7 days
2 9.5%
1–4 weeks
0 0.0%
Over a month
13 62%

How the animals did

Recovered
8 23%
Still unwell when reported
12 34%
Died
1 2.9%
Euthanised
2 5.7%
Not known
12 34%

Problems reported at the same time

Age of the animals

Under 1 year
0
1–3 years
5
4–7 years
9
8–11 years
12
12+ years
9

About this medicine

Type: medicine.

Questions owners ask

Can Phenobarbital cause underdose in dogs?
35 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 149 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Underdose with similar medicines

All reported side effects of Phenobarbital in dogs · Medicines most reported with underdose