Monocytosis after Omeprazole in dogs

The FDA has received 44 reports of monocytosis in dogs after Omeprazole. That is 4.6% of all reports for this medicine, compared with 0.3% across reports for all dog medicines, so it is reported unusually often with this medicine.

44Reports
86%Marked serious
4.5%Recovered
43%Died or euthanised
14 daysTypical onset
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How soon it started

Same day
3 8.6%
1–2 days
5 14%
3–7 days
6 17%
1–4 weeks
12 34%
Over a month
9 26%

How the animals did

Recovered
2 4.5%
Still unwell when reported
19 43%
Died
3 6.8%
Euthanised
16 36%
Not known
4 9.1%

Problems reported at the same time

Age of the animals

Under 1 year
4
1–3 years
9
4–7 years
13
8–11 years
9
12+ years
9

About this medicine

Type: medicine.

Questions owners ask

Can Omeprazole cause monocytosis in dogs?
44 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 14 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Monocytosis with similar medicines

All reported side effects of Omeprazole in dogs · Medicines most reported with monocytosis