Unpalatable after Milbemycin Oxime (Interceptor) in dogs
The FDA has received 45 reports of unpalatable in dogs after Milbemycin Oxime. That is 0.2% of all reports for this medicine, compared with 0.6% across reports for all dog medicines, so it is reported less often than average with this medicine.
45Reports
20%Marked serious
29%Recovered
11%Died or euthanised
90 daysTypical onset
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How soon it started
How the animals did
Problems reported at the same time
Age of the animals
About this medicine
Milbemycin Oxime prevents heartworm and controls some intestinal worms (monthly).
Products with this ingredient include Interceptor. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.
Some herding breeds (for example Collies) carry the MDR1 gene variant and can be more sensitive to this drug class at high doses.
Questions owners ask
- Can Milbemycin Oxime cause unpalatable in dogs?
- 45 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
- How soon after a dose was it reported?
- In half of the reports with dates, it started within 90 days of the first dose.
- What should I do?
- Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).
Unpalatable with similar medicines
- Unpalatable after Ivermectin + Pyrantel (Heartgard Plus) 647 reports · 0.4% of its reports
- Unpalatable after Milbemycin Oxime + Spinosad (Trifexis) 2,574 reports · 2.0% of its reports
- Unpalatable after Milbemycin Oxime + Praziquantel (Interceptor Plus) 183 reports · 0.6% of its reports
- Unpalatable after Ivermectin (Heartgard) 84 reports · 0.7% of its reports
All reported side effects of Milbemycin Oxime in dogs · Medicines most reported with unpalatable