Neurological signs after Metronidazole in dogs

24 reports to the FDA describe neurological signs in dogs given Metronidazole. That is 0.8% of all reports for this medicine, compared with 0.3% across reports for all dog medicines, so it is reported unusually often with this medicine.

24Reports

71%Marked serious

0.0%Recovered

46%Died or euthanised

4 daysTypical onset

How soon it started

Same day

5 26%

1–2 days

3 16%

3–7 days

3 16%

1–4 weeks

3 16%

Over a month

5 26%

How the animals did

Still unwell when reported

10 42%

Euthanised

11 46%

Not known

3 13%

Problems reported at the same time

11 46%

11 46%

11 46%

9 38%

8 33%

7 29%

7 29%

6 25%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Metronidazole treats some bacterial and parasitic gut infections.

Questions owners ask

Can Metronidazole cause neurological signs in dogs?: 24 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 4 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Neurological signs with similar medicines

Neurological signs after Amoxicillin + Clavulanate (Clavamox) 36 reports · 0.7% of its reports
Neurological signs after Cefovecin (Convenia) 42 reports · 1.1% of its reports
Neurological signs after Enrofloxacin (Baytril) 31 reports · 0.8% of its reports

All reported side effects of Metronidazole in dogs · Medicines most reported with neurological signs