Diarrhea after Methadone in dogs

The FDA has received 46 reports of diarrhea in dogs after Methadone. That is 19% of all reports for this medicine, compared with 8.4% across reports for all dog medicines, so it is reported unusually often with this medicine.

46Reports
80%Marked serious
24%Recovered
17%Died or euthanised
2 daysTypical onset
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How soon it started

Same day
12 29%
1–2 days
11 26%
3–7 days
5 12%
1–4 weeks
3 7.1%
Over a month
11 26%

How the animals did

Recovered
11 24%
Still unwell when reported
16 35%
Died
2 4.3%
Euthanised
6 13%
Not known
11 24%

Problems reported at the same time

24 52%
21 46%
11 24%
Hypochloraemia
8 17%
Abnormal ultrasound finding
8 17%

Age of the animals

Under 1 year
3
1–3 years
8
4–7 years
10
8–11 years
20
12+ years
4

About this medicine

Type: medicine.

Questions owners ask

Can Methadone cause diarrhea in dogs?
46 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 2 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Diarrhea with similar medicines

All reported side effects of Methadone in dogs · Medicines most reported with diarrhea