Urine abnormalities after Maropitant (Cerenia) in dogs

The FDA has received 156 reports of urine abnormalities in dogs after Maropitant. That is 1.3% of all reports for this medicine, compared with 0.2% across reports for all dog medicines, so it is reported unusually often with this medicine.

156Reports
72%Marked serious
12%Recovered
38%Died or euthanised
8 daysTypical onset
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How soon it started

Same day
22 17%
1–2 days
23 17%
3–7 days
21 16%
1–4 weeks
31 23%
Over a month
36 27%

How the animals did

Recovered
19 12%
Still unwell when reported
65 42%
Died
16 10%
Euthanised
44 28%
Not known
12 7.7%

Problems reported at the same time

Loss of appetite
106 68%
Liver problems
101 65%
Vomiting
96 62%
Kidney problems
89 57%
Lethargy
75 48%
Proteinuria
61 39%
Death
60 38%
Abnormal ultrasound finding
44 28%

Age of the animals

Under 1 year
12
1–3 years
22
4–7 years
37
8–11 years
52
12+ years
33

About this medicine

Maropitant prevents vomiting and motion sickness.

Products with this ingredient include Cerenia. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Maropitant cause urine abnormalities in dogs?
156 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 8 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

All reported side effects of Maropitant in dogs · Medicines most reported with urine abnormalities