Thrombocytosis after Maropitant (Cerenia) in dogs

97 reports to the FDA describe thrombocytosis in dogs given Maropitant. That is 0.8% of all reports for this medicine, compared with 0.2% across reports for all dog medicines, so it is reported unusually often with this medicine.

97Reports
75%Marked serious
16%Recovered
24%Died or euthanised
25 daysTypical onset
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How soon it started

Same day
11 14%
1–2 days
12 16%
3–7 days
8 11%
1–4 weeks
12 16%
Over a month
33 43%

How the animals did

Recovered
13 13%
Recovered with lasting effects
3 3.1%
Still unwell when reported
41 42%
Died
4 4.1%
Euthanised
19 20%
Not known
17 18%

Problems reported at the same time

Age of the animals

Under 1 year
8
1–3 years
10
4–7 years
20
8–11 years
22
12+ years
36

About this medicine

Maropitant prevents vomiting and motion sickness.

Products with this ingredient include Cerenia. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Maropitant cause thrombocytosis in dogs?
97 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 25 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

All reported side effects of Maropitant in dogs · Medicines most reported with thrombocytosis