Straining to defecate after Maropitant (Cerenia) in dogs

41 reports to the FDA describe straining to defecate in dogs given Maropitant. That is 0.3% of all reports for this medicine, compared with 0.1% across reports for all dog medicines, so it is reported unusually often with this medicine.

41Reports

71%Marked serious

17%Recovered

29%Died or euthanised

11 daysTypical onset

How soon it started

Same day

7 19%

1–2 days

6 17%

3–7 days

4 11%

1–4 weeks

9 25%

Over a month

10 28%

How the animals did

Recovered

7 17%

Still unwell when reported

18 44%

Died

3 7.3%

Euthanised

9 22%

Not known

4 9.8%

Problems reported at the same time

31 76%

28 68%

19 46%

13 32%

12 29%

11 27%

Abnormal radiograph finding

11 27%

Diarrhea

9 22%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Maropitant prevents vomiting and motion sickness.

Products with this ingredient include Cerenia. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Maropitant cause straining to defecate in dogs?: 41 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 11 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

All reported side effects of Maropitant in dogs · Medicines most reported with straining to defecate