Skin slough after Maropitant (Cerenia) in dogs

55 reports to the FDA describe skin slough in dogs given Maropitant. That is 0.5% of all reports for this medicine, compared with 0.1% across reports for all dog medicines, so it is reported unusually often with this medicine.

55Reports

62%Marked serious

24%Recovered

20%Died or euthanised

3 daysTypical onset

How soon it started

Same day

10 20%

1–2 days

13 26%

3–7 days

14 28%

1–4 weeks

7 14%

Over a month

6 12%

How the animals did

Recovered

13 24%

Still unwell when reported

23 42%

Died

6 11%

Euthanised

5 9.1%

Not known

8 15%

Problems reported at the same time

Injection site reaction

27 49%

Swelling

17 31%

Loss of appetite

17 31%

Skin rash or irritation

14 25%

11 20%

10 18%

9 16%

8 15%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Maropitant prevents vomiting and motion sickness.

Products with this ingredient include Cerenia. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Maropitant cause skin slough in dogs?: 55 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 3 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

All reported side effects of Maropitant in dogs · Medicines most reported with skin slough