Restlessness or agitation after Maropitant (Cerenia) in dogs

251 reports to the FDA describe restlessness or agitation in dogs given Maropitant. That is 2.1% of all reports for this medicine, compared with 1.6% across reports for all dog medicines.

251Reports
57%Marked serious
18%Recovered
23%Died or euthanised
1 daysTypical onset
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How soon it started

Same day
91 44%
1–2 days
49 24%
3–7 days
23 11%
1–4 weeks
17 8.3%
Over a month
25 12%

How the animals did

Recovered
44 18%
Still unwell when reported
94 37%
Died
22 8.8%
Euthanised
36 14%
Not known
55 22%

Problems reported at the same time

Vomiting
106 42%
Loss of appetite
104 41%
Lethargy
85 34%
Breathing problems
71 28%
Death
57 23%
Diarrhea
55 22%
Tremors
48 19%
Behaviour change
47 19%

Age of the animals

Under 1 year
19
1–3 years
60
4–7 years
53
8–11 years
55
12+ years
60

About this medicine

Maropitant prevents vomiting and motion sickness.

Products with this ingredient include Cerenia. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Maropitant cause restlessness or agitation in dogs?
251 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 1 day of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Restlessness or agitation with similar medicines

All reported side effects of Maropitant in dogs · Medicines most reported with restlessness or agitation