Lymphadenopathy after Maropitant (Cerenia) in dogs

The FDA has received 74 reports of lymphadenopathy in dogs after Maropitant. That is 0.6% of all reports for this medicine, compared with 0.1% across reports for all dog medicines, so it is reported unusually often with this medicine.

74Reports

70%Marked serious

5.4%Recovered

30%Died or euthanised

8 daysTypical onset

How soon it started

Same day

9 17%

1–2 days

7 13%

3–7 days

10 19%

1–4 weeks

15 28%

Over a month

12 23%

How the animals did

Recovered

4 5.4%

Still unwell when reported

29 39%

Died

8 11%

Euthanised

14 19%

Not known

19 26%

Problems reported at the same time

47 64%

40 54%

38 51%

35 47%

Abnormal ultrasound finding

28 38%

Diarrhea

23 31%

Death

22 30%

Kidney problems

22 30%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Maropitant prevents vomiting and motion sickness.

Products with this ingredient include Cerenia. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Maropitant cause lymphadenopathy in dogs?: 74 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 8 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

All reported side effects of Maropitant in dogs · Medicines most reported with lymphadenopathy