Liver disorder after Maropitant (Cerenia) in dogs

87 reports to the FDA describe liver disorder in dogs given Maropitant. That is 0.7% of all reports for this medicine, compared with 0.1% across reports for all dog medicines, so it is reported unusually often with this medicine.

87Reports

80%Marked serious

3.4%Recovered

55%Died or euthanised

7 daysTypical onset

How soon it started

Same day

13 16%

1–2 days

11 14%

3–7 days

18 23%

1–4 weeks

21 26%

Over a month

17 21%

How the animals did

Recovered

3 3.4%

Still unwell when reported

31 36%

Died

15 17%

Euthanised

33 38%

Not known

5 5.7%

Problems reported at the same time

Liver problems

70 80%

Loss of appetite

62 71%

Vomiting

59 68%

Abnormal ultrasound finding

55 63%

48 55%

40 46%

38 44%

24 28%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Maropitant prevents vomiting and motion sickness.

Products with this ingredient include Cerenia. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Maropitant cause liver disorder in dogs?: 87 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 7 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

All reported side effects of Maropitant in dogs · Medicines most reported with liver disorder