Increased packed cell volume (pcv) after Maropitant (Cerenia) in dogs

87 reports to the FDA describe increased packed cell volume (pcv) in dogs given Maropitant. That is 0.7% of all reports for this medicine, compared with 0.1% across reports for all dog medicines, so it is reported unusually often with this medicine.

87Reports
79%Marked serious
4.6%Recovered
32%Died or euthanised
1 daysTypical onset
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How soon it started

Same day
25 33%
1–2 days
21 28%
3–7 days
10 13%
1–4 weeks
8 11%
Over a month
11 15%

How the animals did

Recovered
4 4.6%
Still unwell when reported
45 52%
Died
18 21%
Euthanised
10 11%
Not known
10 11%

Problems reported at the same time

Age of the animals

Under 1 year
4
1–3 years
26
4–7 years
27
8–11 years
23
12+ years
7

About this medicine

Maropitant prevents vomiting and motion sickness.

Products with this ingredient include Cerenia. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Maropitant cause increased packed cell volume (pcv) in dogs?
87 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 1 day of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

All reported side effects of Maropitant in dogs · Medicines most reported with increased packed cell volume (pcv)