Hypotension after Maropitant (Cerenia) in dogs

The FDA has received 209 reports of hypotension in dogs after Maropitant. That is 1.8% of all reports for this medicine, compared with 0.2% across reports for all dog medicines, so it is reported unusually often with this medicine.

209Reports

89%Marked serious

19%Recovered

45%Died or euthanised

Same dayTypical onset

How soon it started

Same day

113 61%

1–2 days

28 15%

3–7 days

15 8.1%

1–4 weeks

9 4.9%

Over a month

20 11%

How the animals did

Recovered

39 19%

Still unwell when reported

66 32%

Died

41 20%

Euthanised

54 26%

Not known

9 4.3%

Problems reported at the same time

95 45%

94 45%

87 42%

81 39%

76 36%

68 33%

67 32%

59 28%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Maropitant prevents vomiting and motion sickness.

Products with this ingredient include Cerenia. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Maropitant cause hypotension in dogs?: 209 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within the same day of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Hypotension with similar medicines

Hypotension after Capromorelin (Entyce) 24 reports · 1.6% of its reports

All reported side effects of Maropitant in dogs · Medicines most reported with hypotension