Gall bladder & bile duct disorder after Maropitant (Cerenia) in dogs

144 reports to the FDA describe gall bladder & bile duct disorder in dogs given Maropitant. That is 1.2% of all reports for this medicine, compared with 0.1% across reports for all dog medicines, so it is reported unusually often with this medicine.

144Reports

76%Marked serious

9.7%Recovered

42%Died or euthanised

6 daysTypical onset

How soon it started

Same day

29 24%

1–2 days

21 17%

3–7 days

14 12%

1–4 weeks

25 21%

Over a month

32 26%

How the animals did

Recovered

14 9.7%

Still unwell when reported

52 36%

Died

18 13%

Euthanised

42 29%

Not known

18 13%

Problems reported at the same time

Liver problems

115 80%

Loss of appetite

83 58%

Vomiting

82 57%

Abnormal ultrasound finding

81 56%

62 43%

59 41%

54 38%

35 24%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Maropitant prevents vomiting and motion sickness.

Products with this ingredient include Cerenia. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Maropitant cause gall bladder & bile duct disorder in dogs?: 144 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 6 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

All reported side effects of Maropitant in dogs · Medicines most reported with gall bladder & bile duct disorder