Eosinophilia after Maropitant (Cerenia) in dogs

61 reports to the FDA describe eosinophilia in dogs given Maropitant. That is 0.5% of all reports for this medicine, compared with 0.1% across reports for all dog medicines, so it is reported unusually often with this medicine.

61Reports
75%Marked serious
11%Recovered
16%Died or euthanised
4 daysTypical onset
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How soon it started

Same day
11 21%
1–2 days
13 25%
3–7 days
5 9.4%
1–4 weeks
9 17%
Over a month
15 28%

How the animals did

Recovered
6 9.8%
Recovered with lasting effects
1 1.6%
Still unwell when reported
29 48%
Died
3 4.9%
Euthanised
7 11%
Not known
15 25%

Problems reported at the same time

Age of the animals

Under 1 year
17
1–3 years
22
4–7 years
6
8–11 years
9
12+ years
7

About this medicine

Maropitant prevents vomiting and motion sickness.

Products with this ingredient include Cerenia. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Maropitant cause eosinophilia in dogs?
61 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 4 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

All reported side effects of Maropitant in dogs · Medicines most reported with eosinophilia