Elevated symmetrical dimethylarginine (sdma) after Maropitant (Cerenia) in dogs

117 reports to the FDA describe elevated symmetrical dimethylarginine (sdma) in dogs given Maropitant. That is 1.0% of all reports for this medicine, compared with 0.1% across reports for all dog medicines, so it is reported unusually often with this medicine.

117Reports

88%Marked serious

6.0%Recovered

42%Died or euthanised

6 daysTypical onset

How soon it started

Same day

18 19%

1–2 days

21 22%

3–7 days

16 16%

1–4 weeks

16 16%

Over a month

26 27%

How the animals did

Recovered

7 6.0%

Still unwell when reported

51 44%

Died

9 7.7%

Euthanised

40 34%

Not known

10 8.5%

Problems reported at the same time

87 74%

84 72%

63 54%

62 53%

57 49%

49 42%

46 39%

34 29%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Maropitant prevents vomiting and motion sickness.

Products with this ingredient include Cerenia. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Maropitant cause elevated symmetrical dimethylarginine (sdma) in dogs?: 117 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 6 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Elevated symmetrical dimethylarginine (sdma) with similar medicines

Elevated symmetrical dimethylarginine (sdma) after Capromorelin (Entyce) 26 reports · 1.7% of its reports

All reported side effects of Maropitant in dogs · Medicines most reported with elevated symmetrical dimethylarginine (sdma)