Elevated cholesterol (total) after Maropitant (Cerenia) in dogs

The FDA has received 110 reports of elevated cholesterol (total) in dogs after Maropitant. That is 0.9% of all reports for this medicine, compared with 0.3% across reports for all dog medicines, so it is reported unusually often with this medicine.

110Reports

76%Marked serious

4.5%Recovered

45%Died or euthanised

21 daysTypical onset

How soon it started

Same day

15 17%

1–2 days

7 8.0%

3–7 days

11 13%

1–4 weeks

15 17%

Over a month

40 45%

How the animals did

Recovered

5 4.5%

Still unwell when reported

45 41%

Died

16 15%

Euthanised

33 30%

Not known

11 10%

Problems reported at the same time

90 82%

78 71%

64 58%

56 51%

51 46%

49 45%

39 35%

Elevated gamma-glutamyl transferase (ggt)

32 29%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Maropitant prevents vomiting and motion sickness.

Products with this ingredient include Cerenia. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Maropitant cause elevated cholesterol (total) in dogs?: 110 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 21 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Elevated cholesterol (total) with similar medicines

Elevated cholesterol (total) after Capromorelin (Entyce) 20 reports · 1.3% of its reports

All reported side effects of Maropitant in dogs · Medicines most reported with elevated cholesterol (total)