Cardiac enlargement after Maropitant (Cerenia) in dogs

57 reports to the FDA describe cardiac enlargement in dogs given Maropitant. That is 0.5% of all reports for this medicine, compared with 0.1% across reports for all dog medicines, so it is reported unusually often with this medicine.

57Reports

77%Marked serious

7.0%Recovered

53%Died or euthanised

7 daysTypical onset

How soon it started

Same day

13 28%

1–2 days

6 13%

3–7 days

5 11%

1–4 weeks

11 24%

Over a month

11 24%

How the animals did

Recovered

1 1.8%

Recovered with lasting effects

3 5.3%

Still unwell when reported

13 23%

Died

14 25%

Euthanised

16 28%

Not known

10 18%

Problems reported at the same time

37 65%

31 54%

30 53%

25 44%

Abnormal radiograph finding

24 42%

Liver problems

22 39%

Kidney problems

21 37%

Lethargy

18 32%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Maropitant prevents vomiting and motion sickness.

Products with this ingredient include Cerenia. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Maropitant cause cardiac enlargement in dogs?: 57 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 7 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

All reported side effects of Maropitant in dogs · Medicines most reported with cardiac enlargement