Decreased packed cell volume (pcv) after Lyme Vaccine in dogs

The FDA has received 24 reports of decreased packed cell volume (pcv) in dogs after Lyme Vaccine. That is 0.3% of all reports for this medicine, compared with 0.1% across reports for all dog medicines, so it is reported unusually often with this medicine.

24Reports
83%Marked serious
13%Recovered
46%Died or euthanised
12 daysTypical onset
SponsoredWorried about your pet? Ask a veterinarian online, 24/7

How soon it started

Same day
5 28%
1–2 days
2 11%
3–7 days
0 0.0%
1–4 weeks
6 33%
Over a month
5 28%

How the animals did

Recovered
3 13%
Still unwell when reported
6 25%
Died
2 8.3%
Euthanised
9 38%
Not known
4 17%

Problems reported at the same time

Blood problems
16 67%
Vomiting
12 50%
Loss of appetite
12 50%
Death
11 46%
Lethargy
10 42%
Liver problems
8 33%
Decreased red blood cell count
7 29%
Hyperphosphataemia
6 25%

Age of the animals

Under 1 year
5
1–3 years
4
4–7 years
10
8–11 years
4
12+ years
1

About this medicine

Type: vaccine.

Mild, short-lived lethargy, soreness or a small lump at the injection site are the most commonly reported vaccine reactions.

Questions owners ask

Can Lyme Vaccine cause decreased packed cell volume (pcv) in dogs?
24 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 12 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Decreased packed cell volume (pcv) with similar medicines

All reported side effects of Lyme Vaccine in dogs · Medicines most reported with decreased packed cell volume (pcv)