Hypoalbuminaemia after Levothyroxine in dogs

43 reports to the FDA describe hypoalbuminaemia in dogs given Levothyroxine. That is 1.4% of all reports for this medicine, compared with 0.6% across reports for all dog medicines, so it is reported unusually often with this medicine.

43Reports

77%Marked serious

9.3%Recovered

30%Died or euthanised

85 daysTypical onset

How soon it started

Same day

1 4.0%

1–2 days

3 12%

3–7 days

1 4.0%

1–4 weeks

3 12%

Over a month

17 68%

How the animals did

Recovered

2 4.7%

Recovered with lasting effects

2 4.7%

Still unwell when reported

17 40%

Died

2 4.7%

Euthanised

11 26%

Not known

9 21%

Problems reported at the same time

23 53%

19 44%

17 40%

17 40%

16 37%

14 33%

13 30%

12 28%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Levothyroxine treats an underactive thyroid.

Questions owners ask

Can Levothyroxine cause hypoalbuminaemia in dogs?: 43 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 85 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Hypoalbuminaemia with similar medicines

Hypoalbuminaemia after Trilostane (Vetoryl) 84 reports · 0.7% of its reports
Hypoalbuminaemia after Insulin 22 reports · 0.3% of its reports

All reported side effects of Levothyroxine in dogs · Medicines most reported with hypoalbuminaemia