Pyoderma after Ketoconazole in dogs

26 reports to the FDA describe pyoderma in dogs given Ketoconazole. That is 1.2% of all reports for this medicine, compared with 0.2% across reports for all dog medicines, so it is reported unusually often with this medicine.

26Reports

58%Marked serious

15%Recovered

15%Died or euthanised

73 daysTypical onset

How soon it started

Same day

2 9.1%

1–2 days

2 9.1%

3–7 days

2 9.1%

1–4 weeks

2 9.1%

Over a month

14 64%

How the animals did

Recovered

3 12%

Recovered with lasting effects

1 3.8%

Still unwell when reported

11 42%

Died

2 7.7%

Euthanised

2 7.7%

Not known

7 27%

Problems reported at the same time

Lethargy

11 42%

Itching

11 42%

Didn't work as expected

9 35%

Skin rash or irritation

8 31%

8 31%

7 27%

7 27%

6 23%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Type: medicine.

Questions owners ask

Can Ketoconazole cause pyoderma in dogs?: 26 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 73 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Pyoderma with similar medicines

Pyoderma after Melarsomine (Immiticide) 37 reports · 0.2% of its reports
Pyoderma after Cefpodoxime 71 reports · 1.8% of its reports
Pyoderma after Tramadol 24 reports · 0.6% of its reports
Pyoderma after Cephalexin 41 reports · 1.5% of its reports

All reported side effects of Ketoconazole in dogs · Medicines most reported with pyoderma