Ear canal inflammation after Ketoconazole in dogs

24 reports to the FDA describe ear canal inflammation in dogs given Ketoconazole. That is 1.1% of all reports for this medicine, compared with 0.0% across reports for all dog medicines, so it is reported unusually often with this medicine.

24Reports

71%Marked serious

17%Recovered

0.0%Died or euthanised

15 daysTypical onset

How soon it started

Same day

1 5.6%

1–2 days

6 33%

3–7 days

1 5.6%

1–4 weeks

4 22%

Over a month

6 33%

How the animals did

Recovered

4 17%

Still unwell when reported

6 25%

Not known

14 58%

Problems reported at the same time

Ear infection

10 42%

Itching

9 38%

Skin redness

9 38%

Didn't work as expected

8 33%

8 33%

7 29%

7 29%

6 25%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Type: medicine.

Questions owners ask

Can Ketoconazole cause ear canal inflammation in dogs?: 24 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 15 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Ear canal inflammation with similar medicines

Ear canal inflammation after Florfenicol + Mometasone + Terbinafine 107 reports · 3.0% of its reports
Ear canal inflammation after Genta Momet Clotrim 20 reports · 0.9% of its reports

All reported side effects of Ketoconazole in dogs · Medicines most reported with ear canal inflammation