Musculoskeletal disorder after Insulin in dogs

22 reports to the FDA describe musculoskeletal disorder in dogs given Insulin. That is 0.3% of all reports for this medicine, compared with 0.3% across reports for all dog medicines.

22Reports

73%Marked serious

23%Recovered

36%Died or euthanised

19 daysTypical onset

How soon it started

Same day

3 21%

1–2 days

1 7.1%

3–7 days

0 0.0%

1–4 weeks

4 29%

Over a month

6 43%

How the animals did

Recovered

4 18%

Recovered with lasting effects

1 4.5%

Still unwell when reported

7 32%

Died

2 9.1%

Euthanised

6 27%

Not known

2 9.1%

Problems reported at the same time

Weakness

8 36%

Didn't work as expected

7 32%

7 32%

7 32%

6 27%

5 23%

5 23%

5 23%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Insulin treats diabetes.

Questions owners ask

Can Insulin cause musculoskeletal disorder in dogs?: 22 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 19 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Musculoskeletal disorder with similar medicines

Musculoskeletal disorder after Trilostane (Vetoryl) 55 reports · 0.5% of its reports
Musculoskeletal disorder after Phenylpropanolamine (Proin) 20 reports · 0.5% of its reports
Musculoskeletal disorder after Levothyroxine 30 reports · 1.0% of its reports

All reported side effects of Insulin in dogs · Medicines most reported with musculoskeletal disorder