Diabetic ketoacidosis after Insulin in dogs

The FDA has received 45 reports of diabetic ketoacidosis in dogs after Insulin. That is 0.6% of all reports for this medicine, compared with 0.0% across reports for all dog medicines, so it is reported unusually often with this medicine.

45Reports

98%Marked serious

36%Recovered

33%Died or euthanised

10 daysTypical onset

How soon it started

Same day

4 14%

1–2 days

4 14%

3–7 days

5 17%

1–4 weeks

5 17%

Over a month

11 38%

How the animals did

Recovered

15 33%

Recovered with lasting effects

1 2.2%

Still unwell when reported

6 13%

Died

3 6.7%

Euthanised

12 27%

Not known

8 18%

Problems reported at the same time

27 60%

25 56%

20 44%

17 38%

16 36%

Didn't work as expected

15 33%

Diarrhea

14 31%

Liver problems

12 27%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Insulin treats diabetes.

Questions owners ask

Can Insulin cause diabetic ketoacidosis in dogs?: 45 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 10 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Diabetic ketoacidosis with similar medicines

Diabetic ketoacidosis after Trilostane (Vetoryl) 50 reports · 0.4% of its reports

All reported side effects of Insulin in dogs · Medicines most reported with diabetic ketoacidosis