Cyanosis after Hydromorphone in dogs

The FDA has received 26 reports of cyanosis in dogs after Hydromorphone. That is 2.5% of all reports for this medicine, compared with 0.2% across reports for all dog medicines, so it is reported unusually often with this medicine.

26Reports
96%Marked serious
35%Recovered
50%Died or euthanised
Same dayTypical onset
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How soon it started

Same day
19 79%
1–2 days
3 13%
3–7 days
1 4.2%
1–4 weeks
1 4.2%
Over a month
0 0.0%

How the animals did

Recovered
9 35%
Still unwell when reported
3 12%
Died
10 38%
Euthanised
3 12%
Not known
1 3.8%

Problems reported at the same time

13 50%
Respiratory arrest
5 19%

Age of the animals

Under 1 year
1
1–3 years
6
4–7 years
6
8–11 years
6
12+ years
5

About this medicine

Type: medicine.

Questions owners ask

Can Hydromorphone cause cyanosis in dogs?
26 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within the same day of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Cyanosis with similar medicines

All reported side effects of Hydromorphone in dogs · Medicines most reported with cyanosis