Cardiac arrest after Glycopyrrolate in dogs

The FDA has received 21 reports of cardiac arrest in dogs after Glycopyrrolate. That is 17% of all reports for this medicine, compared with 0.2% across reports for all dog medicines, so it is reported unusually often with this medicine.

21Reports
86%Marked serious
33%Recovered
67%Died or euthanised
Same dayTypical onset
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How soon it started

Same day
16 84%
1–2 days
0 0.0%
3–7 days
2 11%
1–4 weeks
1 5.3%
Over a month
0 0.0%

How the animals did

Recovered
7 33%
Died
12 57%
Euthanised
2 9.5%

Problems reported at the same time

14 67%
Apnoea
4 19%
Respiratory arrest
4 19%
Bradycardia
4 19%
Pale mucous membrane
3 14%
2 9.5%
Loose stool
2 9.5%

Age of the animals

Under 1 year
3
1–3 years
4
4–7 years
2
8–11 years
10
12+ years
2

About this medicine

Type: medicine.

Questions owners ask

Can Glycopyrrolate cause cardiac arrest in dogs?
21 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within the same day of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Cardiac arrest with similar medicines

All reported side effects of Glycopyrrolate in dogs · Medicines most reported with cardiac arrest