Neutropenia after Gabapentin in dogs

96 reports to the FDA describe neutropenia in dogs given Gabapentin. That is 1.1% of all reports for this medicine, compared with 0.2% across reports for all dog medicines, so it is reported unusually often with this medicine.

96Reports

66%Marked serious

8.3%Recovered

25%Died or euthanised

21 daysTypical onset

How soon it started

Same day

6 7.7%

1–2 days

12 15%

3–7 days

10 13%

1–4 weeks

18 23%

Over a month

32 41%

How the animals did

Recovered

8 8.3%

Still unwell when reported

47 49%

Died

7 7.3%

Euthanised

17 18%

Not known

17 18%

Problems reported at the same time

45 47%

40 42%

39 41%

39 41%

31 32%

29 30%

28 29%

24 25%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Gabapentin used for pain and to reduce stress or anxiety.

Questions owners ask

Can Gabapentin cause neutropenia in dogs?: 96 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 21 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Neutropenia with similar medicines

Neutropenia after Fluoxetine 25 reports · 1.0% of its reports
Neutropenia after Trazodone 48 reports · 1.9% of its reports

All reported side effects of Gabapentin in dogs · Medicines most reported with neutropenia