Lymphopenia after Gabapentin in dogs

157 reports to the FDA describe lymphopenia in dogs given Gabapentin. That is 1.7% of all reports for this medicine, compared with 0.3% across reports for all dog medicines, so it is reported unusually often with this medicine.

157Reports

82%Marked serious

7.6%Recovered

29%Died or euthanised

16 daysTypical onset

How soon it started

Same day

13 10%

1–2 days

24 19%

3–7 days

19 15%

1–4 weeks

22 17%

Over a month

51 40%

How the animals did

Recovered

12 7.6%

Still unwell when reported

70 45%

Died

12 7.6%

Euthanised

34 22%

Not known

29 18%

Problems reported at the same time

88 56%

81 52%

78 50%

68 43%

63 40%

49 31%

46 29%

45 29%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Gabapentin used for pain and to reduce stress or anxiety.

Questions owners ask

Can Gabapentin cause lymphopenia in dogs?: 157 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 16 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Lymphopenia with similar medicines

Lymphopenia after Fluoxetine 22 reports · 0.9% of its reports
Lymphopenia after Trazodone 41 reports · 1.6% of its reports

All reported side effects of Gabapentin in dogs · Medicines most reported with lymphopenia