Hyperproteinaemia after Gabapentin in dogs

75 reports to the FDA describe hyperproteinaemia in dogs given Gabapentin. That is 0.8% of all reports for this medicine, compared with 0.2% across reports for all dog medicines, so it is reported unusually often with this medicine.

75Reports

81%Marked serious

4.0%Recovered

33%Died or euthanised

14 daysTypical onset

How soon it started

Same day

6 10%

1–2 days

7 12%

3–7 days

11 18%

1–4 weeks

16 27%

Over a month

20 33%

How the animals did

Recovered

2 2.7%

Recovered with lasting effects

1 1.3%

Still unwell when reported

35 47%

Died

6 8.0%

Euthanised

19 25%

Not known

12 16%

Problems reported at the same time

50 67%

45 60%

35 47%

34 45%

34 45%

29 39%

25 33%

20 27%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Gabapentin used for pain and to reduce stress or anxiety.

Questions owners ask

Can Gabapentin cause hyperproteinaemia in dogs?: 75 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 14 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Hyperproteinaemia with similar medicines

Hyperproteinaemia after Trazodone 27 reports · 1.1% of its reports

All reported side effects of Gabapentin in dogs · Medicines most reported with hyperproteinaemia