Decreased urine concentration after Gabapentin in dogs

The FDA has received 159 reports of decreased urine concentration in dogs after Gabapentin. That is 1.8% of all reports for this medicine, compared with 0.4% across reports for all dog medicines, so it is reported unusually often with this medicine.

159Reports

60%Marked serious

5.7%Recovered

14%Died or euthanised

23 daysTypical onset

How soon it started

Same day

15 12%

1–2 days

15 12%

3–7 days

13 10%

1–4 weeks

31 24%

Over a month

54 42%

How the animals did

Recovered

9 5.7%

Still unwell when reported

92 58%

Died

6 3.8%

Euthanised

16 10%

Not known

36 23%

Problems reported at the same time

74 47%

73 46%

60 38%

55 35%

54 34%

47 30%

41 26%

31 19%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Gabapentin used for pain and to reduce stress or anxiety.

Questions owners ask

Can Gabapentin cause decreased urine concentration in dogs?: 159 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 23 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Decreased urine concentration with similar medicines

Decreased urine concentration after Selegiline (Anipryl) 27 reports · 0.7% of its reports
Decreased urine concentration after Trazodone 31 reports · 1.2% of its reports
Decreased urine concentration after Clomipramine (Clomicalm) 24 reports · 1.6% of its reports

All reported side effects of Gabapentin in dogs · Medicines most reported with decreased urine concentration