Cardiac enlargement after Furosemide in dogs

The FDA has received 39 reports of cardiac enlargement in dogs after Furosemide. That is 2.6% of all reports for this medicine, compared with 0.1% across reports for all dog medicines, so it is reported unusually often with this medicine.

39Reports

87%Marked serious

5.1%Recovered

38%Died or euthanised

5 daysTypical onset

How soon it started

Same day

7 28%

1–2 days

5 20%

3–7 days

1 4.0%

1–4 weeks

3 12%

Over a month

9 36%

How the animals did

Recovered with lasting effects

2 5.1%

Still unwell when reported

11 28%

Died

8 21%

Euthanised

7 18%

Not known

11 28%

Problems reported at the same time

Breathing problems

21 54%

Cough

17 44%

Abnormal radiograph finding

17 44%

16 41%

15 38%

13 33%

12 31%

10 26%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Type: medicine.

Questions owners ask

Can Furosemide cause cardiac enlargement in dogs?: 39 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 5 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Cardiac enlargement with similar medicines

Cardiac enlargement after Melarsomine (Immiticide) 66 reports · 0.3% of its reports
Cardiac enlargement after Diphenhydramine 20 reports · 0.4% of its reports
Cardiac enlargement after Enalapril 21 reports · 1.3% of its reports

All reported side effects of Furosemide in dogs · Medicines most reported with cardiac enlargement