Liver failure after Firocoxib (Previcox) in dogs

The FDA has received 27 reports of liver failure in dogs after Firocoxib. That is 0.3% of all reports for this medicine, compared with 0.1% across reports for all dog medicines, so it is reported unusually often with this medicine.

27Reports
37%Marked serious
7.4%Recovered
63%Died or euthanised
–Typical onset
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How the animals did

Recovered
1 3.7%
Recovered with lasting effects
1 3.7%
Still unwell when reported
2 7.4%
Died
12 44%
Euthanised
5 19%
Not known
6 22%

Problems reported at the same time

Age of the animals

Under 1 year
0
1–3 years
2
4–7 years
5
8–11 years
11
12+ years
8

About this medicine

Firocoxib relieves pain and inflammation from arthritis.

Products with this ingredient include Previcox. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

NSAIDs can affect the stomach, liver and kidneys. Vets usually recommend blood tests before and during long-term use.

Questions owners ask

Can Firocoxib cause liver failure in dogs?
27 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Liver failure with similar medicines

All reported side effects of Firocoxib in dogs · Medicines most reported with liver failure