Duodenal ulcer after Firocoxib (Previcox) in dogs

The FDA has received 71 reports of duodenal ulcer in dogs after Firocoxib. That is 0.9% of all reports for this medicine, compared with 0.0% across reports for all dog medicines, so it is reported unusually often with this medicine.

71Reports

87%Marked serious

17%Recovered

56%Died or euthanised

7 daysTypical onset

How soon it started

Same day

2 3.8%

1–2 days

3 5.7%

3–7 days

22 42%

1–4 weeks

16 30%

Over a month

10 19%

How the animals did

Recovered

11 15%

Recovered with lasting effects

1 1.4%

Still unwell when reported

10 14%

Died

26 37%

Euthanised

14 20%

Not known

9 13%

Problems reported at the same time

Vomiting

48 68%

Death

38 54%

Loss of appetite

36 51%

Intestinal perforation

34 48%

28 39%

26 37%

22 31%

21 30%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Firocoxib relieves pain and inflammation from arthritis.

Products with this ingredient include Previcox. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

NSAIDs can affect the stomach, liver and kidneys. Vets usually recommend blood tests before and during long-term use.

Questions owners ask

Can Firocoxib cause duodenal ulcer in dogs?: 71 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 7 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Duodenal ulcer with similar medicines

Duodenal ulcer after Carprofen (Rimadyl) 55 reports · 0.1% of its reports
Duodenal ulcer after Deracoxib (Deramaxx) 46 reports · 0.4% of its reports

All reported side effects of Firocoxib in dogs · Medicines most reported with duodenal ulcer