Increased packed cell volume (pcv) after Famotidine in dogs

The FDA has received 23 reports of increased packed cell volume (pcv) in dogs after Famotidine. That is 0.9% of all reports for this medicine, compared with 0.1% across reports for all dog medicines, so it is reported unusually often with this medicine.

23Reports

70%Marked serious

0.0%Recovered

30%Died or euthanised

1 daysTypical onset

How soon it started

Same day

7 35%

1–2 days

6 30%

3–7 days

1 5.0%

1–4 weeks

3 15%

Over a month

3 15%

How the animals did

Still unwell when reported

12 52%

Died

5 22%

Euthanised

2 8.7%

Not known

4 17%

Problems reported at the same time

17 74%

16 70%

15 65%

14 61%

12 52%

10 43%

10 43%

7 30%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Type: medicine.

Questions owners ask

Can Famotidine cause increased packed cell volume (pcv) in dogs?: 23 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 1 day of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Increased packed cell volume (pcv) with similar medicines

Increased packed cell volume (pcv) after Melarsomine (Immiticide) 21 reports · 0.1% of its reports

All reported side effects of Famotidine in dogs · Medicines most reported with increased packed cell volume (pcv)