Enlarged lymph node (localised) after Famotidine in dogs

The FDA has received 25 reports of enlarged lymph node (localised) in dogs after Famotidine. That is 0.9% of all reports for this medicine, compared with 0.1% across reports for all dog medicines, so it is reported unusually often with this medicine.

25Reports

76%Marked serious

16%Recovered

32%Died or euthanised

4 daysTypical onset

How soon it started

Same day

6 27%

1–2 days

2 9.1%

3–7 days

5 23%

1–4 weeks

6 27%

Over a month

3 14%

How the animals did

Recovered

2 8.0%

Recovered with lasting effects

2 8.0%

Still unwell when reported

9 36%

Died

1 4.0%

Euthanised

7 28%

Not known

4 16%

Problems reported at the same time

15 60%

14 56%

11 44%

10 40%

9 36%

9 36%

8 32%

7 28%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Type: medicine.

Questions owners ask

Can Famotidine cause enlarged lymph node (localised) in dogs?: 25 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 4 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Enlarged lymph node (localised) with similar medicines

Enlarged lymph node (localised) after Diphenhydramine 26 reports · 0.6% of its reports
Enlarged lymph node (localised) after Tigilanol Tiglate 35 reports · 1.7% of its reports

All reported side effects of Famotidine in dogs · Medicines most reported with enlarged lymph node (localised)