Urinary incontinence after Estriol in dogs

The FDA has received 90 reports of urinary incontinence in dogs after Estriol. That is 4.4% of all reports for this medicine, compared with 0.6% across reports for all dog medicines, so it is reported unusually often with this medicine.

90Reports
84%Marked serious
22%Recovered
5.6%Died or euthanised
14 daysTypical onset
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How soon it started

Same day
22 29%
1–2 days
5 6.7%
3–7 days
2 2.7%
1–4 weeks
27 36%
Over a month
19 25%

How the animals did

Recovered
20 22%
Still unwell when reported
42 47%
Died
1 1.1%
Euthanised
4 4.4%
Not known
23 26%

Problems reported at the same time

Age of the animals

Under 1 year
1
1–3 years
17
4–7 years
18
8–11 years
24
12+ years
28

About this medicine

Type: medicine.

Questions owners ask

Can Estriol cause urinary incontinence in dogs?
90 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 14 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Urinary incontinence with similar medicines

All reported side effects of Estriol in dogs · Medicines most reported with urinary incontinence