Inappropriate urination after Enalapril in dogs

The FDA has received 21 reports of inappropriate urination in dogs after Enalapril. That is 1.3% of all reports for this medicine, compared with 0.5% across reports for all dog medicines, so it is reported unusually often with this medicine.

21Reports

62%Marked serious

19%Recovered

24%Died or euthanised

30 daysTypical onset

How soon it started

Same day

2 15%

1–2 days

1 7.7%

3–7 days

2 15%

1–4 weeks

2 15%

Over a month

6 46%

How the animals did

Recovered

4 19%

Still unwell when reported

3 14%

Euthanised

5 24%

Not known

9 43%

Problems reported at the same time

9 43%

8 38%

6 29%

5 24%

5 24%

4 19%

4 19%

4 19%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Type: medicine.

Questions owners ask

Can Enalapril cause inappropriate urination in dogs?: 21 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 30 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Inappropriate urination with similar medicines

Inappropriate urination after Melarsomine (Immiticide) 86 reports · 0.4% of its reports
Inappropriate urination after Polysulfated Glycosaminoglycan 49 reports · 0.9% of its reports
Inappropriate urination after Diphenhydramine 70 reports · 1.5% of its reports
Inappropriate urination after Butorphanol 42 reports · 0.9% of its reports
Inappropriate urination after Cefpodoxime 56 reports · 1.4% of its reports
Inappropriate urination after Tramadol 79 reports · 2.1% of its reports
Inappropriate urination after Florfenicol + Mometasone + Terbinafine 49 reports · 1.4% of its reports
Inappropriate urination after Desoxycorticosterone Pivalate 74 reports · 2.2% of its reports
Inappropriate urination after Propofol 22 reports · 0.7% of its reports
Inappropriate urination after Isoflurane 28 reports · 1.0% of its reports

All reported side effects of Enalapril in dogs · Medicines most reported with inappropriate urination