Anxiety after Doxycycline in dogs

41 reports to the FDA describe anxiety in dogs given Doxycycline. That is 1.0% of all reports for this medicine, compared with 0.5% across reports for all dog medicines, so it is reported unusually often with this medicine.

41Reports

61%Marked serious

24%Recovered

22%Died or euthanised

31 daysTypical onset

How soon it started

Same day

7 21%

1–2 days

5 15%

3–7 days

0 0.0%

1–4 weeks

4 12%

Over a month

17 52%

How the animals did

Recovered

10 24%

Still unwell when reported

14 34%

Died

2 4.9%

Euthanised

7 17%

Not known

8 20%

Problems reported at the same time

13 32%

11 27%

10 24%

10 24%

9 22%

9 22%

9 22%

8 20%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Doxycycline treats bacterial and tick-borne infections.

Questions owners ask

Can Doxycycline cause anxiety in dogs?: 41 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 31 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Anxiety with similar medicines

Anxiety after Amoxicillin + Clavulanate (Clavamox) 56 reports · 1.0% of its reports
Anxiety after Cefovecin (Convenia) 38 reports · 1.0% of its reports
Anxiety after Enrofloxacin (Baytril) 44 reports · 1.2% of its reports
Anxiety after Metronidazole 50 reports · 1.6% of its reports

All reported side effects of Doxycycline in dogs · Medicines most reported with anxiety