Pr-liver, lesion(s) after Dirlotapide in dogs

The FDA has received 21 reports of pr-liver, lesion(s) in dogs after Dirlotapide. That is 0.7% of all reports for this medicine, compared with 0.3% across reports for all dog medicines, so it is reported unusually often with this medicine.

21Reports

0.0%Marked serious

0.0%Recovered

86%Died or euthanised

–Typical onset

How the animals did

Still unwell when reported

1 4.8%

Died

18 86%

Not known

2 9.5%

Problems reported at the same time

18 86%

13 62%

13 62%

13 62%

8 38%

7 33%

4 19%

Pr-spleen, lesion(s)

4 19%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Type: medicine.

Questions owners ask

Can Dirlotapide cause pr-liver, lesion(s) in dogs?: 21 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Pr-liver, lesion(s) with similar medicines

Pr-liver, lesion(s) after Polysulfated Glycosaminoglycan 22 reports · 0.4% of its reports
Pr-liver, lesion(s) after Cefpodoxime 28 reports · 0.7% of its reports
Pr-liver, lesion(s) after Medetomidine 23 reports · 1.1% of its reports
Pr-liver, lesion(s) after Etodolac 55 reports · 2.9% of its reports

All reported side effects of Dirlotapide in dogs · Medicines most reported with pr-liver, lesion(s)