Systemic disorder after Desoxycorticosterone Pivalate in dogs

The FDA has received 26 reports of systemic disorder in dogs after Desoxycorticosterone Pivalate. That is 0.8% of all reports for this medicine, compared with 0.2% across reports for all dog medicines, so it is reported unusually often with this medicine.

26Reports

69%Marked serious

19%Recovered

15%Died or euthanised

59 daysTypical onset

How soon it started

Same day

2 18%

1–2 days

0 0.0%

3–7 days

0 0.0%

1–4 weeks

2 18%

Over a month

7 64%

How the animals did

Recovered

5 19%

Still unwell when reported

3 12%

Euthanised

4 15%

Not known

14 54%

Problems reported at the same time

10 38%

7 27%

5 19%

5 19%

High sodium-potassium ratio (na:k ratio)

5 19%

Diarrhea

4 15%

Loss of appetite

4 15%

Death

4 15%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Type: medicine.

Questions owners ask

Can Desoxycorticosterone Pivalate cause systemic disorder in dogs?: 26 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 59 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Systemic disorder with similar medicines

Systemic disorder after Melarsomine (Immiticide) 48 reports · 0.2% of its reports
Systemic disorder after Diphenhydramine 28 reports · 0.6% of its reports
Systemic disorder after Tramadol 30 reports · 0.8% of its reports
Systemic disorder after Famotidine 23 reports · 0.9% of its reports

All reported side effects of Desoxycorticosterone Pivalate in dogs · Medicines most reported with systemic disorder