Hypothyroidism after Desoxycorticosterone Pivalate in dogs

The FDA has received 26 reports of hypothyroidism in dogs after Desoxycorticosterone Pivalate. That is 0.8% of all reports for this medicine, compared with 0.2% across reports for all dog medicines, so it is reported unusually often with this medicine.

26Reports

42%Marked serious

7.7%Recovered

15%Died or euthanised

–Typical onset

How the animals did

Recovered with lasting effects

2 7.7%

Still unwell when reported

6 23%

Died

2 7.7%

Euthanised

2 7.7%

Not known

14 54%

Problems reported at the same time

8 31%

7 27%

7 27%

6 23%

5 19%

5 19%

5 19%

4 15%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Type: medicine.

Questions owners ask

Can Desoxycorticosterone Pivalate cause hypothyroidism in dogs?: 26 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Hypothyroidism with similar medicines

Hypothyroidism after Cefpodoxime 20 reports · 0.5% of its reports
Hypothyroidism after Dirlotapide 22 reports · 0.8% of its reports

All reported side effects of Desoxycorticosterone Pivalate in dogs · Medicines most reported with hypothyroidism